The first four-part formula built to target the Flare Cycle: strain, swell, leak, flare, then start all over again.
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$64.95
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Make the 7 a.m. bathroom just a bathroom again
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Kiwi Extract supports flow before straining starts
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Diosmin firms the wall while hesperidin calms the fire
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Horse chestnut: flares came back 3x less in our 14 trials
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GMP certified, vegan, third-party tested, 2 small capsules
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Diosmin+Hesperidin 4-in-1 | Four-Layer Support | Horse Chestnut + Kiwifruit
Regular price
$39.95
Regular price
$39.95
Sale price
$64.95
Unit price/ per
SAVE 38%
Sold out
STOCK UPDATE: Buy 3 Get 2 Free just sold out again. Buy 2 Get 1 Free is still available, but it's going fast.
90-Day Guarantee
Waiting through another flare is the real risk. Try it for 90 days. If your pattern does not change, we refund every penny and cover return shipping.
The Science Behind It
The Flare Cycle starts below the surface. Straining raises pressure, the vein swells, weakened walls leak, and another flare begins. Creams can soothe the skin, but they cannot reach that whole loop.
This four-part formula targets each step. In a human study, the body absorbed 57.9% of micronized diosmin (ground 20x finer) versus just 32.7% of regular diosmin. Hesperidin helps calm swelling and irritation. In a 2026 trial, adding horse chestnut cut the number of people whose flares came back within 3 months from 23.5% to just 7.0%. In a U.S. trial, kiwifruit eased constipation with fewer side effects than prunes or fiber powder.
Shipping & Returns
Free shipping on every order. Ships within 24 hours from our U.S. warehouse in a plain, discreet box. Tracking is emailed immediately. Full refund within 90 days, and we cover return shipping.
Is It Safe?
People in clinical studies handled these ingredients well. Two small, easy-to-digest capsules. Kiwifruit provides gentle digestive support. No laxatives. No stimulants. Nothing messy to apply, and no tube to carry around all day.
Ingredients
• Micronized Diosmin, 900 mg (Citrus sinensis): makes the vein wall firm and strong. • Micronized Hesperidin, 100 mg (Citrus sinensis): calms swelling. Paired 9:1, just like in the studies. • Horse Chestnut Seed Extract (Aesculus hippocastanum): gives you escin to help seal leaky veins. • Kiwifruit Extract (Actinidia deliciosa): gives you actinidin to keep things moving. • Two small capsules. Nothing hidden. Nothing extra.
Frequently Asked Questions
On the weekly shot? Had this since the baby? Buying for a parent? Tried everything already? Your most direct questions are answered below.
Six years of Prep H and Tucks pads. I'd get two good days, then right back to it. Three weeks on this and I went a full week without a single flare. I actually forgot about it for a day. That hasn't happened in years.
"Six years of flares. Six years of Prep H, sitz baths, witch hazel pads, and still waking up to bleeding every few weeks. My doctor said to eat more fiber. I was already eating fiber. My sister found this and I almost didn't try it. I was done trusting new products. Week two, the bleeding slowed down. By week four, I went through a full work week without a single flare. I sat through a three-hour drive last weekend and didn't shift once. That hasn't happened in years."
★★★★★
James R.✓ Verified
"I tried every hemorrhoid supplement on Amazon"
"I burned through four different Amazon brands. Nothing. Not even a change. What sold me on this was the micronized form. I looked it up and it's the same compound they prescribe in Europe, just at the right dose. Most Amazon supplements don't even tell you how much diosmin is actually in them. Three weeks in, the itching stopped first. Then the swelling went down. My wife asked what changed. I told her two small capsules and four ingredients. Should have found this years ago."
★★★★★
Rachel M.✓ Verified
"Another hemorrhoid 'cure' — sure"
"I've been burned by hemorrhoid products before. Overpriced blends with mystery amounts. So when my daughter ordered me a 3-pack, I told her to return it. She didn't. I started taking it just to prove it wouldn't work. By week three, the flare I was expecting after every bathroom trip didn't come. Week four, same thing. I'm on bottle two now. I've had one minor flare in six weeks. Before this it was every five to seven days like clockwork. I'm angry nobody told me about this years ago."
#1 Doctor Recommended
★★★★★
I see the same loop every week. A hard bowel movement starts the swelling, the wall leaks, the flare calms, then the next strain starts it again.
Think of a worn garden hose. Pressure makes the weak spot bulge and leak. Cream may cool the outside, but it cannot firm the wall underneath.
Micronized diosmin and hesperidin have decades of medical use in Europe. In the U.S., most patients hear about fiber and creams, not vein support.
Most products touch one corner of the problem. They soothe the skin or move the bowel. They do not address straining, inflammation, wall strength, and leakage together.
In a 2026 randomized trial, adding escin to micronized flavonoids reduced 3-month recurrence to 7.0% versus 23.5%, with bleeding stopping sooner.
The people I hear from most are using weekly shots, living with changes since childbirth, or taking medicines that slow the bowel. Kiwifruit addresses that first trigger.
Dr. Sarah Mitchell, MDBoard-Certified Gastroenterologist & Vascular Health Specialist · 22 Years in Practice
4 Ingredients. 4 Jobs. Built for the Flare Cycle.
Micronized Diosmin, 900 mg
Diosmetin 7-O-rutinoside · from Citrus sinensis (sweet orange) peel
Structure
This is the backbone. Diosmin is a citrus flavonoid that goes straight to the vein wall, where the bulging starts, and helps make it firm and strong. Ours is micronized: ground 20x finer than regular diosmin. In a human study, the body absorbed 57.9% of micronized diosmin versus just 32.7% of the regular kind. Doctors in Europe have used this same 9:1 formula as medicine for over 50 years.
Micronized Hesperidin, 100 mg
Hesperetin 7-O-rutinoside · from Citrus sinensis (sweet orange) peel
Fire Control
Hesperidin puts out the fire at the source: the inflammation behind the swelling, itching, and bleeding. It is the parent flavonoid of diosmin, found in orange peel. Here the two are paired in the exact 9:1 ratio used in clinical studies. Diosmin rebuilds the wall. Hesperidin calms the angry tissue around it. That is real relief, not a cream that fades in an hour.
Horse Chestnut Seed Extract
Aesculus hippocastanum · natural source of escin (aescin)
Seal
This is the piece most formulas leave out. Horse chestnut seed gives you escin, a plant compound that helps tighten leaky vessel walls so fluid stays where it belongs. In a 2026 clinical trial, adding escin to micronized flavonoids meant flares came back for just 7.0% of people, versus 23.5% without it. Ottoman riders fed these Balkan seeds to their horses. European healers later used them for heavy legs and piles.
Kiwifruit Extract
Actinidia deliciosa · natural source of the enzyme actinidin
Flow
Kiwifruit stops the problem before it starts. It softens stool and keeps things moving, so you are not straining and slamming pressure into the vein every morning. Its natural enzyme, actinidin, helps your gut break down protein. In a U.S. clinical trial, green kiwifruit worked as well as prunes and psyllium fiber, with the fewest side effects. It began as China's “monkey peach” before reaching New Zealand.
🥝 Pathway 1: Stop the StrainKiwifruit (Actinidia deliciosa) softens stool and eases every morning trip. Less pushing means less pressure, so the next flare never gets a chance to start.
🔥 Pathway 2: Firm the Wall + Calm the FireMicronized diosmin (from Citrus sinensis) tightens the stretched vein wall. Hesperidin works beside it to cool the inflammation behind swelling, itching, and bleeding.
🛡️ Pathway 3: Seal the LeakHorse chestnut (Aesculus hippocastanum) delivers escin to help seal leaky vessels, the weak spot that lets the cycle come back. Four ingredients. Four jobs. One loop, targeted from every side.
Why A Capsule — Not A Cream
THE PROBLEM:
The cream works where you put it, for a few hours. Then the next strain raises pressure, the vein swells, the wall leaks, and the flare returns. So you carry the tube to work and reapply in a bathroom stall. You are soothing one moment while the Flare Cycle keeps turning underneath.
THE RESEARCH:
A review of 14 studies found these plant compounds reduced bleeding and flare comebacks. In a 2-month trial against a sugar pill, 40% of daily users had a flare versus 70% on the sugar pill, and flares lasted 2.6 days versus 4.6. In a 2026 trial, adding escin reduced 3-month recurrence to 7.0% versus 23.5% and shortened median bleeding time from 4 days to 2.
THE SOLUTION:
Two small capsules with breakfast. Kiwifruit supports flow. Diosmin supports the wall. Hesperidin calms the fire. Horse chestnut supports the leak. Four layers work on the loop from the inside, with no mess, no reapplying, and no tube hidden in your purse.
WHY IT HAS TO BE ORAL:
The weak vein wall sits beneath the surface. A cream, pad, or suppository can soothe what you feel, but it cannot travel through the bloodstream to support that wall. It also cannot soften what is coming tomorrow morning. An oral routine can support both sides of the loop: digestive flow before the strain and the vein after pressure hits. Two small capsules with breakfast reach the part the bathroom cabinet cannot, while the products you already use can stay available for surface comfort.
Why Everything Else Failed You
Most products work on one corner of the Flare Cycle. Yours needs support at all four.
Other Hemorrhoid Products
RCM Living Diosmin+Hesperidin 4-in-1
What it targets: Surface symptoms only
All four points of the loop
The straining: Ignored or harsh laxatives
Kiwifruit support, no laxatives
Coming back: Returns every few weeks
Escin trial: 7.0% vs 23.5%
Clinical evidence: Few controlled cream trials
12+ trials and a review of 14 studies
Dose transparency: Hidden blend, no amounts listed
Free shipping · 90-day money-back guarantee · Every ingredient disclosed
2 Small Capsules. Once a Day. With Breakfast.
Daily Dose
Take 2 small, easy-to-swallow capsules with breakfast. Kiwifruit supports comfortable digestion. Same time every morning. That is the whole routine.
Don't Stop After the First Good Week
The first change can arrive in 1 to 2 weeks. Keep going. Stop too early and the old loop can start turning again. Wall support builds over 2 to 3 months.
What to Expect First
Easier mornings may come first. Then less bleeding, less swelling, and longer gaps between flares. The change is often a pattern, not one dramatic moment.
Works Alongside What You Already Use
Keep your fiber, sitz bath, or cream. Stay on your weekly shot and prescribed medicines. This supports the digestive-flow and vein-wall steps those routines may not address.
Built for the Person Living This Loop.
“Creams help for a few hours, then I am right back to it.”
The tube stays in your purse. You know which bathroom at work has a locking stall. You reapply, feel better, then the next hard bowel movement starts everything again. That is the Flare Cycle. Surface comfort has a place, but it cannot firm the wall, calm the fire, support the leak, and reduce the strain underneath.
“The shot is working. The bathroom is not.”
The shot pen is still in the fridge because you are not giving up the progress. But slower digestion can bring constipation, and more fiber can feel like cement when fluid intake falls short. Kiwifruit leads this formula by supporting softer, easier mornings. Keep the plan that is helping you. Address the loop that is making the bathroom feel like glass.
“I tried Amazon supplements. They did absolutely nothing.”
Look at the labels. Hidden blends. No micronized form. No tested 9:1 ratio. One ingredient aimed at one part of the problem. This formula uses four clearly named layers for digestive flow, vein-wall structure, inflammation, and vessel leakage. You can see the diosmin and hesperidin amounts before you swallow anything.
“I have had this since my first baby.”
You were told it was part of motherhood, like stretch marks. It was not. Pregnancy put pressure on the veins, the wall stretched, and the flare kept returning because nobody addressed the leak. Horse chestnut provides escin for vessel support while the other three layers work on the strain, the wall, and the fire.
“I have not told anyone. Or I am buying for my parent.”
The donut cushion stays in the car. Long drives get shorter. The keys are still on the hook at noon because the bathroom took an hour. Nobody has to look or apply anything. Two small capsules go down with breakfast, whether you are taking them yourself or setting them beside Mom or Dad's morning routine.
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
4 Layers, 1 Routine
Third-Party Tested
When You'll Feel It (Honest Timeline)
DAYS 1-7—Foundation
Kiwifruit starts supporting softer, easier mornings, so the first trip may feel less difficult. At the same time, micronized diosmin, hesperidin, and horse chestnut begin supporting the wall, inflammation, and leakage. Some people notice less bleeding during this first week. Others notice only that they are straining less. Both are early signs that the pattern is shifting.
WEEK 2-3—First Signs
You stop holding your breath before sitting down. Bleeding may ease. In the 2026 escin trial, median bleeding time was 2 days with escin added versus 4 without it. You sit through a meeting, finish a drive, or drink your morning coffee without shifting every few minutes.
WEEK 4-6—Real Change
Flares may arrive less often and feel milder when they do. You forget about the problem for a day, then realize forgetting is the change. In a 2-month trial against a sugar pill, 40% of daily users had a flare versus 70% on the sugar pill. The gap starts showing up in ordinary life, not just in a symptom diary.
MONTH 2-3—Compound Effect
The pattern that returned every 5 to 7 days may stretch into weeks. In the 2-month trial, flares lasted 2.6 days versus 4.6 on the sugar pill. In the 2026 escin trial, recurrence at 3 months was 7.0% with escin added versus 23.5% without it. Daily support compounds while the loop loses momentum.
MONTH 3+—New Normal
Mornings become mornings again. The bathroom no longer decides when you leave the house. Two small capsules with breakfast are the whole routine. Once the old strain, swell, leak, flare pattern stops controlling the week, going back to one-hour fixes is not worth it.
Why Everything Else Failed. Why This Won't.
What's Actually Happening:
The weekly shot slows digestion. Pregnancy once put intense pressure on the veins. Years, pain medicine, and slower bowels add more strain. Then the same four beats repeat: strain, swell, leak, flare. It calms, but the weak point remains. The next hard morning starts it again. The answer is not another surface layer. It is supporting every point of the loop together.
Why Nothing Else Worked:
Preparation H: Numbs the surface for a few hours. It never reaches the weakened vein wall underneath.
Witch Hazel Pads / Tucks: Tighten and cool the skin. The pressure and leakage below the surface remain.
Fiber and Laxatives: Fiber needs enough fluid. Laxatives can force movement, but neither supports the vein wall after straining.
Amazon Supplements: Hidden blends hide doses and often target one layer. You cannot compare them with the studied compounds.
“Give It Time”: Time does not support a leaking vessel wall. Without a new routine, the Flare Cycle keeps turning.
What This Formula Does:
Phase 1: Days 1-7
Kiwifruit starts supporting softer stool and less straining. Diosmin, hesperidin, and horse chestnut begin supporting the wall, inflammation, and leakage beneath the surface.
Phase 2: Weeks 2-4
Vein tone gets daily support. Vessel leakage and inflammation are addressed. Bleeding may ease, and flares may become shorter and less intense.
Phase 3: Months 1-3
The compound effect becomes visible: 40% versus 70% flare rates and 2.6 versus 4.6 flare days in one micronized flavonoid trial. In the 2026 escin trial, recurrence was 7.0% versus 23.5%. The loop is supported at every step.
Frequently Asked Questions
Straight answers for the questions you may be too tired or embarrassed to ask.
Most labels hide the amounts inside a secret blend. Many do not say whether the diosmin is micronized or paired with hesperidin in the studied 9:1 ratio. Others target only one part of the problem. This formula names all four layers. Diosmin supports the wall. Hesperidin supports inflammation. Horse chestnut supports leakage. Kiwifruit supports easier bowel movements. You can see both listed flavonoid amounts before you buy.
Fiber, water, and creams are the usual U.S. playbook. They can help with stool consistency and surface comfort. In parts of Europe, micronized diosmin and hesperidin are also used as medicine for vein-related symptoms. This formula adds horse chestnut for vessel support and kiwifruit for digestive flow. It is built around the Flare Cycle that basic surface advice may leave untouched.
Preparation H can make a flare more comfortable by working on the surface. This formula has a different job. It supports the digestive-flow and vein-side factors beneath the surface: straining, wall structure, inflammation, and leakage. Keep the cream if it helps you through a difficult hour. Use the daily capsules for the part the cream cannot reach.
Easier mornings may come first as kiwifruit supports digestive flow. Less bleeding can follow in the first 1 to 2 weeks, then less swelling and longer gaps between flares. Full vein support builds over 2 to 3 months. In one 2-month trial, daily users had fewer and shorter flares than the sugar-pill group. Watch the pattern, not one bathroom trip.
No capsule can promise that hemorrhoids will never return. This formula is designed to support the four factors that keep the cycle moving. In a 2026 trial, adding escin to micronized flavonoids reduced 3-month recurrence to 7.0% versus 23.5% without escin. Daily use matters. Think of it like brushing your teeth: the routine protects the progress you have made.
FDA prescribing information for semaglutide states that it delays gastric emptying and that constipation is a common side effect. More dry fiber can feel worse when fluid intake is not keeping up. Kiwifruit supports softer stool and less straining without adding a stimulant laxative to this formula. The other three layers support the vein after pressure hits. Address the bathroom pattern alongside the routine that is helping you.
Micronized diosmin and hesperidin have been used in parts of Europe for decades, but they were never marketed here like creams and wipes. Most U.S. shelves still focus on surface comfort. This formula starts with the studied 9:1 flavonoid compound, then adds horse chestnut for vessel support and kiwifruit for digestive flow. Four layers address the full loop instead of one visible symptom.
It is two small, easy-to-digest capsules with breakfast. No stimulant. No laxative. Nothing to apply and nobody has to look. It can sit beside fiber or a stool softener because those support a different part of the routine. Two capsules. One simple morning step.
Long-standing symptoms do not make you invisible. Pregnancy may have stretched the veins years ago, but daily support can still address the wall, inflammation, leakage, and straining that keep the pattern going. The clinical evidence includes people with recurring symptoms, not only first-time flares. The 90-day window gives the routine enough time to show whether your flare pattern is changing.
Use it consistently for up to 90 days. If your flare pattern does not meaningfully change, contact us. We will return every penny and cover return shipping. No store credit. No long form. No risk beyond giving the routine a fair chance.
The Flare Cycle Is Turning Today.
Every hard morning you wait puts fresh pressure on the same weakened wall.
My doctor told me to just use fiber and Prep H. That was five years ago. I'm on month two of this and I went three full weeks without a flare. Three weeks. I used to get them every four or five days. I sat through my grandson's entire baseball game on a metal bleacher last Saturday. Didn't move once. That alone was worth it.
Bought: 2 Bottles
Deborah W.
Verified Buyer
Austin, TX · Age 51
★★★★★3 weeks ago
I'd been dealing with hemorrhoids since my second pregnancy. Nine years. Creams, pads, sitz baths, prescription suppositories — the whole rotation. Nothing broke the cycle. My sister sent me an article about diosmin being a prescription medicine in Europe and I started researching. Found this. Four weeks in and the bleeding stopped first. Then the swelling went down. I'm on month three now. I still take it every morning. I don't plan on stopping.
Bought: 4 Bottles
James S.
Verified Buyer
Tampa, FL · Age 58
★★★★★1 month ago
I'm a truck driver. Eight hours in a seat every day. The hemorrhoids got so bad I was dreading every shift. I tried three different supplements from Amazon. I can't even remember all their names. Zero difference. This was different within two weeks. Less bleeding. Less swelling after my shift. By week six I stopped carrying the cushion. I keep a bottle in my cab now.
Bought: 3 Bottles
Gerald T.
Verified Buyer
Denver, CO · Age 54
★★★★★1 month ago
I didn't tell anyone about my hemorrhoids for eight years. Not my wife, not my doctor. I just managed it with Prep H and hoped nobody noticed me shifting in my chair at work. When I finally looked into it, I found out this stuff is literally a prescription medicine in France. Same compound, same dose. I figured if doctors in Europe prescribe it, it's worth trying. Five weeks in and the flare cycle that ran like clockwork every week has slowed to maybe once every three weeks. And when it does happen, it's mild. One day instead of four.
Bought: 2 Bottles
Karen U.
Verified Buyer
Phoenix, AZ · Age 48
★★★★★6 weeks ago
The shot was working. I was down 31 pounds. But the bathroom turned into a fight every single morning. Fiber made it feel like cement. Then the bleeding started, and I was scared to go. I started 2 small capsules with breakfast. By week two, mornings were easier. By week five, the bleeding had stopped. I kept the shot. I just stopped dreading 7 a.m.
Bought: 2 Bottles
Jessica D.
Verified Buyer
Atlanta, GA · Age 64
★★★★★5 weeks ago
Everyone told me it was just part of being a mom. Eleven years of creams, pads, and sitz baths. I'd get a good week, then a flare, like clockwork. What finally made sense was the Flare Cycle. Nothing I used ever touched the vein wall. A month in, the flares are smaller and further apart. I wish someone had told me this after my first baby.
Bought: 1 Bottle
Mary N.
Verified Buyer
Memphis, TN · Age 46
★★★★★7 weeks ago
My father would never say a word. I just noticed he stopped going on drives and sat on a cushion at dinner. He takes a lot of pills, so I liked that these were only 2 small capsules. No laxative, nothing to apply. I set them beside his coffee every morning. Six weeks later he asked to drive to the lake. That was the sign for me.
Bought: 2 Bottles
Angela F.
Verified Buyer
Indianapolis, IN · Age 58
★★★★★1 week ago
I'm on my feet for 12 hours, and I'm the one who knows better. I'd still be in the staff bathroom reapplying cream between patients. I read the escin trial and the micronized diosmin studies, and I was impressed. Three weeks in, I made it through a full shift without thinking about it once. The 90-day guarantee made it an easy yes.
Bought: 2 Bottles
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